DUB - InvivoChem

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Signaling Pathways
Apoptosis
- ♦ Bcl-2(14)
- ♦ p53(11)
- ♦ Caspase(12)
- ♦ TNFa(12)
- ♦ Mdm2(17)
- ♦ c-RET(4)
- ♦ IAP(6)
- ♦ PERK(4)
- ♦ PD-1/PD-L1(15)
- ♦ Survivin(1)
- ♦ Apoptosis(1)
PI3K/Akt/mTOR
- ♦ PI3K (64)
- ♦ Akt (22)
- ♦ mTOR (21)
- ♦ GSK-3 (17)
- ♦ ATM/ATR (0)
- ♦ PDK-1 (4)
- ♦ S6 kinase (6)
- ♦ AMPK (8)
- ♦ DNA-PK (3)
Epigenetics
- ♦ HDAC(3)
- ♦ HIF(7)
- ♦ PARP(0)
- ♦ JAK(33)
- ♦ Aurora Kinase(23)
- ♦ Histone Acetyltransferase (6)
- ♦ Histone Demethylase(10)
- ♦ Histone Methyltransferase (29)
- ♦ DNA Methyltransferase(8)
- ♦ Epigenetic Reader Domain (19)
- ♦ Sirtuin (11)
- ♦ Pim (6)
MAPK
- ♦ MEK(18)
- ♦ ERK(9)
- ♦ Raf(16)
- ♦ JNK(9)
- ♦ p38 MAPK(17)
Protein Tyrosine Kinase
- ♦ VEGFR (46)
- ♦ EGFR (42)
- ♦ PDGFR(12)
- ♦ c-MET (15)
- ♦ HER-2(2)
- ♦ ALK(10)
- ♦ FLT3 (8)
- ♦ FGFR (10)
- ♦ IFG-1R(8)
- ♦ c-Kit(3)
- ♦ Tie-2(1)
- ♦ CSF-1R(2)
- ♦ TAM Receptor (6)
- ♦ Trk receptor(3)
- ♦ c-RET(0)
Angiogenesis
- ♦ VEGFR (1)
- ♦ EGFR (0)
- ♦ PDGFR (0)
- ♦ HIF (1)
- ♦ HER-2 (0)
- ♦ JAK (0)
- ♦ FLT3 (0)
- ♦ FGFR (0)
- ♦ BTK (8)
- ♦ Syk(6)
- ♦ FAK (8)
- ♦ Src (8)
- ♦ Bcr-Abl (10)
- ♦ VDA (3)
Proteases
- ♦ Proteasome (13)
- ♦ Cysteine Protease (11)
- ♦ Serine Protease(6)
- ♦ Gamma-secretase (10)
- ♦ HCV Protease (5)
- ♦ HIV Protease(7)
- ♦ MMP (6)
- ♦ DPP-4 (8)
- ♦ Caspase (0)
- ♦ Acyltransferase(1)
NF-kB
- ♦ NOD1 (2)
- ♦ IκB/IKK(15)
- ♦ NF-κB(15)
- ♦ HDAC (0)
Autophagy
- ♦ Autophagy (24)
- ♦ LRRK2 (6)
JAK/STAT
- ♦ JAK (1)
- ♦ STAT(0)
- ♦ EGFR (3)
- ♦ Pim (1)
Metabolism
- ♦ PDE (26)
- ♦ P450 (e.g. CYP) (25)
- ♦ PPAR (16)
- ♦ Phospholipase (8)
- ♦ DHFR(6)
- ♦ Dehydrogenase (19)
- ♦ HSP (20)
- ♦ Carbonic Anhydrase (16)
- ♦ MAO (0)
- ♦ FAAH (6)
- ♦ CETP(4)
- ♦ Transferase (8)
- ♦ HMG-CoA Reductase(11)
- ♦ Hydroxylase (8)
- ♦ IDO (6)
- ♦ Retinoid Receptor (5)
- ♦ Factor Xa (4)
- ♦ AhR (3)
- ♦ Ferroptosis(3)
- ♦ Casein Kinase (4)
- ♦ NAMPT (3)
- ♦ Glucosylceramide Synthase(1)
Neuronal Signaling
- ♦ 5-HT Receptor (1)
- ♦ COX (40)
- ♦ GluR (19)
- ♦ Adrenergic Receptor(1)
- ♦ AChR Receptor (56)
- ♦ Histamine Receptor (0)
- ♦ Dopamine Receptor (1)
- ♦ Opioid Receptor (0)
- ♦ GABA Receptor (3)
- ♦ P-gp (0)
- ♦ CaMK (8)
- ♦ P2 Receptor (7)
- ♦ OX Receptor (0)
- ♦ MT Receptor (0)
- ♦ BACE (2)
- ♦ Gamma-secretase (0)
- ♦ Beta Amyloid (5)
- ♦ Monoamine Oxidase(1)
Ubiquitin
- ♦ E2 conjugating (1)
- ♦ p97 (3)
- ♦ E3 Ligase (0)
- ♦ DUB (9)
- ♦ Proteasome (0)
Stem Cells/Wnt
- ♦ Hedgehog/Smoothened ROCK (1)
- ♦ ROCK(0)
- ♦ Wnt/beta-catenin (2)
- ♦ Gamma-secretase (0)
- ♦ Casein Kinase (1)
- ♦ TGF–beta/Smad (0)
- ♦ STAT (9)
- ♦ JAK (0)
- ♦ GSK-3 (0)
DNA Damage
- ♦ Telomerase(2)
- ♦ Topoisomerase (36)
- ♦ DNA/RNA Synthesis (74)
- ♦ HDAC (39)
- ♦ ATM/ATR (14)
- ♦ PARP (31)
- ♦ Sirtuin (0)
- ♦ DNA Stain(1)
GPCR & G Protein
- ♦ cAMP (2)
- ♦ Adenosine Receptor (19)
- ♦ Vasopressin Receptor (5)
- ♦ CXCR (7)
- ♦ CaSR (3)
- ♦ PAFR (2)
- ♦ CGRP Receptor (1)
- ♦ LPA Receptor (2)
- ♦ SGLT (5)
- ♦ S1P Receptor (8)
- ♦ Endothelin Receptor (7)
- ♦ Cannabinoid Receptor (9)
- ♦ 5-HT Receptor (79)
- ♦ Adrenergic Receptor (65)
- ♦ Histamine Receptor (47)
- ♦ Dopamine Receptor (39)
- ♦ Opioid Receptor (13)
- ♦ Hedgehog/Smoothened ROCK (11)
- ♦ OX Receptor (8)
- ♦ MT Receptor (2)
- ♦ Guanylate Cyclase(3)
- ♦ LPL Receptor(1)
- ♦ NPY receptor(1)
TGF-beta/Smad
- ♦ MT Receptor (20)
- ♦ Bcr-Abl (0)
- ♦ ROCK (20)
- ♦ PKC (10)
Cell Cycle
- ♦ CDK (45)
- ♦ Rho (13)
- ♦ PLK (10)
- ♦ Chk (6)
- ♦ Aurora Kinase (0)
- ♦ ROCK (2)
- ♦ PD-1/PD-L1 (0)
- ♦ c-Myc (3)
- ♦ Wee1 (1)
- ♦ APC (1)
- ♦ HSP(2)
Cytoskeletal Signaling
- ♦ Bcr-Abl(1)
- ♦ Wnt/beta-catenin (10)
- ♦ PKC (1)
- ♦ FAK(0)
- ♦ HSP (1)
- ♦ Dynamin (3)
- ♦ PAK (4)
- ♦ Integrin (9)
- ♦ Microtubule Associated(25)
- ♦ Kinesin (6)
Transmembrane
- ♦ P-gp (6)
- ♦ Proton Pump (10)
- ♦ GABA Receptor (11)
- ♦ Sodium Channel (28)
- ♦ Potassium Channel (16)
- ♦ Calcium Channel (34)
- ♦ ATPase (0)
- ♦ CRM1 (1)
- ♦ TRPV (0)
- ♦ CFTR (0)
- ♦ OCT (0)
- ♦ Amino Acid Transporter(2)
- ♦ Monocarboxylate Transporter(1)
Endocrinology & Hormones
- ♦ Opioid Receptor (0)
- ♦ Glucocorticoid Receptor(5)
- ♦ Estrogen/progestogen Receptor (43)
- ♦ Androgen Receptor (15)
- ♦ RAAS (27)
- ♦ Aromatase(5)
- ♦ GPR(8)
- ♦ 5-alpha Reductase (2)
Microbiology
- ♦ HCV Protease (1)
- ♦ HIV Protease (0)
- ♦ CCR (1)
- ♦ Reverse Transcriptase(27)
- ♦ Integrase (0)
- ♦ Bacterial(4)
- ♦ Anti-infection(0)
Others
- ♦ gp120/CD4 (2)
- ♦ FXR(4)
- ♦ PKA (2)
- ♦ Thrombin (4)
- ♦ Liver X receptor (3)
- ♦ IL Receptor (0)
- ♦ Others 1(365)
- ♦ Others 2(433)
- ♦ Others 3(331)
- ♦ Others 4(295)
- ♦ Others 5(250)
- ♦ Others 6(572)
- ♦ Others 7(232)
New Products
- ♦ New1(25335)
- ♦ New2(7404)
- ♦ New3(9983)
- ♦ New4(21)
Immunology/Inflammation
- ♦ STING(3)
- ♦ Glucocorticoid Receptor(1)
- ♦ Arginase(2)
- ♦ TLR(3)
ADC Related
- ♦ ADC Linker(3)
Metabolic Enzyme/Protease
- ♦ Phosphodiesterase(PDE)(4)
- ♦ Aminopeptidase(1)
- ♦ Endogenous Metabolite(2)
- ♦ Phospholipase(1)
Anti-infection
- ♦ HSV(1)
- ♦ Fungal(7)
- ♦ Influenza Virus(3)
- ♦ Bacterial(39)
- ♦ HBV(1)
- ♦ HCV Protease(1)
- ♦ HIV(3)
- ♦ RABV(1)
- ♦ Parasite(3)
Vitamin D Related/Nuclear Receptor
- ♦ Progesterone Receptor(1)
- ♦ Glucocorticoid Receptor(2)
- ♦ Estrogen Receptor/ERR(1)
PROTAC
- ♦ PROTAC Linkers(40)
Transmembrane Transporters
- ♦ TRP(1)
- ♦ ATPase(2)

Product Type
Natural Products
- ♦ Natural Products 1(446)
Peptides
- ♦ Peptides 1(1995)
Antibodies
Amino Acids
- ♦ Amino Acids 1(389)
PROTACs
- ♦ PROTACs 1(39)
Fine Intermediates/Building Blocks
Others

PR-619

Catalog No： V1322

CAS No. (CAS Registry Number)： 2645-32-1

Price： $0/g

Description: PR-619 (PR619; PR 619) is a novel, cell-permeable, non-selective and reversible inhibitor of the deubiquitinylating enzymes (DUBs) with potential antineoplastic activity. It inhibits DUB ...

P5091 (P005091)

Catalog No： V1323

CAS No. (CAS Registry Number)： 882257-11-6

Price： $0/g

Description: P5091 (also called P5091; P-005091; P-5091; P005091) is a novel, potent, specific and selective inhibitor of ubiquitin-specific protease 7 (USP7) with potential anticancer ...

IU1

Catalog No： V1324

CAS No. (CAS Registry Number)： 314245-33-5

Price： $0/g

Description: IU1 (IU-1; IU 1) is a cell-permeable, reversible and selective proteasome inhibitor of human USP14 with the potential to be used for treating neurodegenerative disease. It inhibits U...

TCID

Catalog No： V1325

CAS No. (CAS Registry Number)： 30675-13-9

Price： $0/g

Description: TCID (4,5,6,7-tetrachloro-1H-indene-1,3(2H)-dione) is a novel and potent DUB (deubiquitinylating enzymes) inhibitor that inhibits ubiquitin C-terminal hydrolase L3 with an IC50 of 0.6 μM....

LDN-57444

Catalog No： V1326

CAS No. (CAS Registry Number)： 668467-91-2

Price： $0/g

Description: LDN-57444 (LDN57444; LDN 57444) is a potent, reversible, and competitive proteasome inhibitor for Uch-L1 (ubiquitin C-terminal hydrolase-L1) with the potential to treat PD-Parkinson's...

P22077

Catalog No： V1328

CAS No. (CAS Registry Number)： 1247819-59-5

Price： $0/g

Description: P22077 (P-22077; P 22077) is a potent, cell-permeable and selective inhibitor of ubiquitin-specific protease USP7 (ubiquitin-specific protease 7) with potential antitumor a...

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