Unfolded Protein Response

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Signaling Pathways
Apoptosis
- ♦ Bcl-2(37)
- ♦ p53(20)
- ♦ Caspase(25)
- ♦ TNFa(20)
- ♦ Mdm2(22)
- ♦ c-RET(4)
- ♦ IAP(9)
- ♦ PERK(4)
- ♦ PD-1/PD-L1(15)
- ♦ Survivin(3)
- ♦ Apoptosis(88)
- ♦ RIP kinase(18)
- ♦ ROS(1)
- ♦ Cytohesin(1)
- ♦ Ras(3)
- ♦ Thymidylate Synthase(4)
- ♦ DAPK(1)
- ♦ ASK(1)
- ♦ FKBP(2)
- ♦ Ferroptosis(9)
- ♦ TRADD(1)
- ♦ PKD(3)
- ♦ c-Myc(2)
- ♦ TNF Receptor (2)
PI3K/Akt/mTOR
- ♦ PI3K (108)
- ♦ Akt (42)
- ♦ mTOR (31)
- ♦ GSK-3 (24)
- ♦ ATM/ATR (3)
- ♦ PDK-1 (4)
- ♦ S6 kinase (6)
- ♦ AMPK (19)
- ♦ DNA-PK (10)
- ♦ PTEN(3)
- ♦ PDPK1(3)
- ♦ NUDIX(3)
- ♦ PDHK(3)
- ♦ PI4K(5)
- ♦ PP2A(1)
- ♦ MELK(4)
- ♦ PIKfyve(1)
Epigenetics
- ♦ HDAC(12)
- ♦ HIF(7)
- ♦ PARP(0)
- ♦ JAK(56)
- ♦ Aurora Kinase(24)
- ♦ Histone Acetyltransferase (14)
- ♦ Histone Demethylase(28)
- ♦ Histone Methyltransferase (87)
- ♦ DNA Methyltransferase(14)
- ♦ Epigenetic Reader Domain (72)
- ♦ Sirtuin (19)
- ♦ Pim (6)
- ♦ PKC(17)
- ♦ SMYD(1)
- ♦ MAT(5)
- ♦ MicroRNA(2)
- ♦ AMPK(6)
- ♦ Protein Arginine Deiminase(3)
- ♦ EZH1/2(1)
- ♦ MLL(1)
MAPK
- ♦ MEK(32)
- ♦ ERK(31)
- ♦ Raf(30)
- ♦ JNK(22)
- ♦ p38 MAPK(34)
- ♦ RSK(5)
- ♦ Mixed Lineage Kinase(5)
- ♦ KLF(4)
- ♦ MNK(4)
- ♦ MAP4K(4)
- ♦ MAP3K(2)
- ♦ MK2(3)
Protein Tyrosine Kinase
- ♦ VEGFR (80)
- ♦ EGFR (66)
- ♦ PDGFR(25)
- ♦ c-MET (34)
- ♦ HER-2(2)
- ♦ ALK(24)
- ♦ FLT3 (17)
- ♦ FGFR (29)
- ♦ IFG-1R(11)
- ♦ c-Kit(10)
- ♦ Tie-2(1)
- ♦ CSF-1R(4)
- ♦ TAM Receptor (10)
- ♦ Trk receptor(9)
- ♦ c-RET(0)
- ♦ Axl(2)
- ♦ Bcr-Abl(10)
- ♦ Ephrin Receptor(2)
- ♦ Pyk2(1)
- ♦ c-Fms(8)
- ♦ DDR(1)
- ♦ IGF-1R(0)
- ♦ HER2(2)
- ♦ Src(14)
- ♦ Syk(10)
- ♦ DYRK(5)
- ♦ FAK(5)
- ♦ Btk(23)
- ♦ Itk(2)
- ♦ Mertk(1)
- ♦ RET(7)
- ♦ SHP2(5)
- ♦ Insulin Receptor(3)
- ♦ ROS Kinase(1)
- ♦ BMX Kinase(1)
- ♦ Discoidin Domain Receptor(2)
Angiogenesis
- ♦ VEGFR (1)
- ♦ EGFR (1)
- ♦ PDGFR (0)
- ♦ HIF (5)
- ♦ HER-2 (1)
- ♦ JAK (0)
- ♦ FLT3 (2)
- ♦ FGFR (0)
- ♦ BTK (14)
- ♦ Syk(8)
- ♦ FAK (8)
- ♦ Src (9)
- ♦ Bcr-Abl (11)
- ♦ VDA (3)
- ♦ ALK(1)
- ♦ 5-alpha Reductase(1)
Proteases
- ♦ Proteasome (15)
- ♦ Cysteine Protease (15)
- ♦ Serine Protease(9)
- ♦ Gamma-secretase (10)
- ♦ HCV Protease (12)
- ♦ HIV Protease(9)
- ♦ MMP (10)
- ♦ DPP-4 (15)
- ♦ Caspase (0)
- ♦ Acyltransferase(1)
- ♦ Tyrosinase(1)
- ♦ Glutaminase(8)
- ♦ Thrombin(8)
- ♦ 3C-Like Protease(1)
- ♦ Neprilysin(2)
NF-kB
- ♦ NOD1 (2)
- ♦ IκB/IKK(28)
- ♦ NF-κB(59)
- ♦ HDAC (0)
- ♦ ROS(1)
- ♦ Keap1-Nrf2(8)
Autophagy
- ♦ Autophagy (63)
- ♦ LRRK2 (15)
- ♦ ULK(6)
- ♦ Mitophagy(1)
- ♦ OGA(1)
JAK/STAT
- ♦ JAK (13)
- ♦ STAT(13)
- ♦ EGFR (36)
- ♦ Pim (14)
Metabolism
- ♦ PDE (38)
- ♦ P450 (e.g. CYP) (31)
- ♦ PPAR (22)
- ♦ Phospholipase (12)
- ♦ DHFR(8)
- ♦ Dehydrogenase (33)
- ♦ HSP (22)
- ♦ Carbonic Anhydrase (19)
- ♦ MAO (5)
- ♦ FAAH (12)
- ♦ CETP(4)
- ♦ Transferase (12)
- ♦ HMG-CoA Reductase(11)
- ♦ Hydroxylase (9)
- ♦ IDO (12)
- ♦ Retinoid Receptor (9)
- ♦ Factor Xa (5)
- ♦ AhR (7)
- ♦ Ferroptosis(4)
- ♦ Casein Kinase (14)
- ♦ NAMPT (7)
- ♦ Glucosylceramide Synthase(2)
- ♦ Aldose Reductase(2)
- ♦ ATP-citrate lyase(1)
- ♦ Carbohydrate Metabolism(3)
- ♦ FXR(12)
- ♦ IAP(1)
- ♦ Lipoxygenase(11)
- ♦ Mitochondrial Metabolism(3)
- ♦ PCSK9(4)
- ♦ Phosphorylase(2)
- ♦ Serine hydrolase(1)
- ♦ SGK(2)
- ♦ Vitamin(15)
- ♦ Acyltransferase(2)
- ♦ CAR(2)
- ♦ ROR(6)
- ♦ PRMT(2)
- ♦ PGC-1α(2)
- ♦ Lipase(3)
- ♦ OXPHOS(3)
- ♦ Peroxidases(3)
- ♦ Phosphatase(6)
- ♦ Decarboxylase(4)
- ♦ Prostaglandin Receptor(1)
- ♦ Serine/threonin kinase(6)
- ♦ Fatty Acid Synthase(6)
- ♦ SCD(1)
- ♦ THR(4)
- ♦ Glutathione(1)
- ♦ CPT(2)
- ♦ Acetyl-CoA Carboxylase(5)
- ♦ AChR(2)
- ♦ cGAS(2)
- ♦ CPSase(1)
- ♦ AdipoR(2)
- ♦ GLUT(2)
- ♦ PKM(3)
- ♦ Mitochondrial pyruvate carrier(1)
- ♦ ACSS2(1)
- ♦ FABP(1)
- ♦ Xanthine Oxidase(1)
- ♦ Thrombopoietin Receptor(1)
- ♦ Thioredoxin Reductase(1)
- ♦ SHIP(1)
Neuronal Signaling
- ♦ 5-HT Receptor (5)
- ♦ COX (42)
- ♦ GluR (24)
- ♦ Adrenergic Receptor(11)
- ♦ AChR Receptor (63)
- ♦ Histamine Receptor (8)
- ♦ Dopamine Receptor (9)
- ♦ Opioid Receptor (5)
- ♦ GABA Receptor (19)
- ♦ P-gp (0)
- ♦ CaMK (12)
- ♦ P2 Receptor (9)
- ♦ OX Receptor (1)
- ♦ MT Receptor (0)
- ♦ BACE (3)
- ♦ Gamma-secretase (0)
- ♦ Beta Amyloid (19)
- ♦ Monoamine Oxidase(13)
- ♦ P2Y Receptor(1)
- ♦ NMDAR(7)
- ♦ γ-secretase(3)
- ♦ Calcium Channel(6)
- ♦ Serotonin Transporter(7)
- ♦ Transthyretin (TTR)(2)
- ♦ Notch(8)
- ♦ ChE(10)
- ♦ BChE(2)
- ♦ Glucosylceramide Synthase(3)
- ♦ AAK1(2)
- ♦ Dopamine Transporter(4)
- ♦ Sigma Receptor(15)
- ♦ Tau Protein(1)
- ♦ Beta-secretase(6)
- ♦ Imidazoline Receptor(4)
- ♦ Adenosine Kinase(2)
- ♦ α-synuclein(1)
Ubiquitin
- ♦ E2 conjugating (2)
- ♦ p97 (5)
- ♦ E3 Ligase (11)
- ♦ DUB (20)
- ♦ Proteasome (0)
- ♦ E1 Activating(5)
- ♦ SUMO(1)
Stem Cells/Wnt
- ♦ Hedgehog/Smoothened ROCK (5)
- ♦ ROCK(0)
- ♦ Wnt/beta-catenin (30)
- ♦ Gamma-secretase (0)
- ♦ Casein Kinase (4)
- ♦ TGF–beta/Smad (1)
- ♦ STAT (9)
- ♦ JAK (0)
- ♦ GSK-3 (2)
- ♦ Smo(5)
- ♦ PKA(6)
- ♦ Oct(3)
- ♦ Porcupine(3)
- ♦ Hippo (MST)(2)
- ♦ YAP(5)
- ♦ SFRP(1)
- ♦ Stemness kinase(1)
DNA Damage
- ♦ Telomerase(3)
- ♦ Topoisomerase (54)
- ♦ DNA/RNA Synthesis (115)
- ♦ HDAC (52)
- ♦ ATM/ATR (18)
- ♦ PARP (51)
- ♦ Sirtuin (7)
- ♦ DNA Stain(4)
- ♦ Nucleoside Antimetabolite/Analog(7)
- ♦ DNA alkylator(10)
- ♦ p97(3)
- ♦ CRISPR/Cas9(1)
- ♦ SMN(1)
- ♦ HSP(11)
- ♦ RNR(2)
- ♦ OGG1(2)
- ♦ RAD51(4)
- ♦ PARG(1)
GPCR & G Protein
- ♦ cAMP (8)
- ♦ Adenosine Receptor (38)
- ♦ Vasopressin Receptor (8)
- ♦ CXCR (35)
- ♦ CaSR (8)
- ♦ PAFR (2)
- ♦ CGRP Receptor (6)
- ♦ LPA Receptor (2)
- ♦ SGLT (8)
- ♦ S1P Receptor (12)
- ♦ Endothelin Receptor (13)
- ♦ Cannabinoid Receptor (24)
- ♦ 5-HT Receptor (141)
- ♦ Adrenergic Receptor (113)
- ♦ Histamine Receptor (76)
- ♦ Dopamine Receptor (77)
- ♦ Opioid Receptor (30)
- ♦ Hedgehog/Smoothened ROCK (11)
- ♦ OX Receptor (23)
- ♦ MT Receptor (2)
- ♦ Guanylate Cyclase(15)
- ♦ LPL Receptor(18)
- ♦ NPY receptor(1)
- ♦ Angiotensin Receptor(21)
- ♦ Free Fatty Acid Receptor(10)
- ♦ GnRH Receptor(10)
- ♦ GPR(21)
- ♦ Leukotriene Receptor(8)
- ♦ mAChR(32)
- ♦ Neurotensin Receptor(4)
- ♦ Prostaglandin Receptor(40)
- ♦ Sigma Receptor(1)
- ♦ PAR(10)
- ♦ CCR(21)
- ♦ GCGR(27)
- ♦ GHSR(6)
- ♦ GPCR19(3)
- ♦ LTR(1)
- ♦ mGluR(29)
- ♦ PKD(2)
- ♦ Ras(22)
- ♦ CCK receptor(4)
- ♦ Melatonin Receptor(5)
- ♦ Formyl Peptide Receptor(2)
- ♦ G protein-coupled Bile Acid Receptor(2)
- ♦ Melanocortin Receptor(5)
- ♦ Neurokinin Receptor(12)
- ♦ Oxytocin Receptor(3)
- ♦ Somatostatin Receptor(3)
- ♦ Adenylate Cyclase(3)
- ♦ Bradykinin Receptor(3)
- ♦ P2Y Receptor(7)
- ♦ Urotensin Receptor(1)
- ♦ TSH Receptor(2)
- ♦ PKG(2)
- ♦ RGS Protein(3)
- ♦ Glucagon Receptor(2)
- ♦ TAAR(1)
- ♦ Neuropeptide Y Receptor(5)
- ♦ Motilin Receptor(1)
- ♦ CRFR(3)
- ♦ APJ(1)
- ♦ EBI2(1)
- ♦ Bombesin Receptor(2)
- ♦ GPR109A(2)
- ♦ MRGPR(2)
TGF-beta/Smad
- ♦ MT Receptor (20)
- ♦ Bcr-Abl (0)
- ♦ ROCK (23)
- ♦ PKC (16)
- ♦ TGF-β Receptor(13)
- ♦ TGF-beta/Smad(6)
Cell Cycle
- ♦ CDK (105)
- ♦ Rho (19)
- ♦ PLK (19)
- ♦ Chk (12)
- ♦ Aurora Kinase (7)
- ♦ ROCK (8)
- ♦ PD-1/PD-L1 (0)
- ♦ c-Myc (6)
- ♦ Wee1 (2)
- ♦ APC (3)
- ♦ HSP(6)
- ♦ Microtubule/Tubulin(40)
- ♦ HDAC(18)
- ♦ PPAR(24)
- ♦ Eukaryotic Initiation Factor(5)
- ♦ Topoisomerase(14)
- ♦ Ras(5)
- ♦ Mps1(5)
- ♦ Kinesin(8)
- ♦ PAK(5)
- ♦ PERK(1)
- ♦ Antifolate(3)
- ♦ TOPK(5)
- ♦ PARP(0)
- ♦ LIMK(5)
- ♦ G-quadruplex(2)
- ♦ PFKFB(4)
- ♦ BMI-1(2)
- ♦ Mad2(1)
- ♦ Nur77(2)
- ♦ p21(1)
- ♦ SRPK(2)
Cytoskeletal Signaling
- ♦ Bcr-Abl(1)
- ♦ Wnt/beta-catenin (10)
- ♦ PKC (1)
- ♦ FAK(0)
- ♦ HSP (3)
- ♦ Dynamin (3)
- ♦ PAK (4)
- ♦ Integrin (28)
- ♦ Microtubule Associated(26)
- ♦ Kinesin (6)
- ♦ MLCK(2)
- ♦ Gap Junction Protein(5)
- ♦ Myosin(3)
- ♦ Cardiac Myosin(1)
- ♦ Arp2/3 Complex(1)
- ♦ TACC3(1)
Transmembrane
- ♦ P-gp (11)
- ♦ Proton Pump (18)
- ♦ GABA Receptor (38)
- ♦ Sodium Channel (64)
- ♦ Potassium Channel (75)
- ♦ Calcium Channel (82)
- ♦ ATPase (14)
- ♦ CRM1 (2)
- ♦ TRPV (0)
- ♦ CFTR (9)
- ♦ OCT (0)
- ♦ Amino Acid Transporter(3)
- ♦ Apical Sodium-Dependent Bile Acid Transporter(3)
- ♦ Chloride Channel(6)
- ♦ GlyT(3)
- ♦ P2 Receptor(2)
- ♦ TRP Channel(42)
- ♦ BCRP(3)
- ♦ CD markers(4)
- ♦ HCN Channel(3)
- ♦ iGluR(37)
- ♦ Interleukins(1)
- ♦ nAChR(20)
- ♦ OAT(1)
- ♦ SGLT(9)
- ♦ Monocarboxylate Transporter(2)
- ♦ Adrenergic Receptor(1)
- ♦ P2X Receptor(9)
- ♦ CRAC Channel(3)
- ♦ Monoamine Transporter(4)
- ♦ Piezo Channel(2)
- ♦ Aquaporin(2)
- ♦ EAAT(2)
- ♦ NKCC(1)
- ♦ VDAC(4)
- ♦ NHE(3)
- ♦ URAT1(4)
- ♦ Na+/K+ ATPase(2)
- ♦ Na+/Ca2+ Exchanger(2)
- ♦ ATP Synthase(1)
- ♦ Calmodulin(1)
- ♦ MTP(2)
- ♦ Na+/HCO3- Cotransporter(1)
Endocrinology & Hormones
- ♦ Opioid Receptor (0)
- ♦ Glucocorticoid Receptor(7)
- ♦ Estrogen/progestogen Receptor (50)
- ♦ Androgen Receptor (23)
- ♦ RAAS (27)
- ♦ Aromatase(6)
- ♦ GPR(9)
- ♦ 5-alpha Reductase (2)
- ♦ Adrenergic Receptor(2)
- ♦ Mineralocorticoid Receptor(3)
- ♦ ACE(3)
- ♦ TSH Receptor(2)
- ♦ THR(1)
Microbiology
- ♦ HCV Protease (0)
- ♦ HIV Protease (2)
- ♦ CCR (2)
- ♦ Reverse Transcriptase(35)
- ♦ Integrase (1)
- ♦ Bacterial(13)
- ♦ Anti-infection(7)
- ♦ HSV(1)
- ♦ Influenza Virus(2)
- ♦ RSV(1)
- ♦ β-lactamase(1)
- ♦ Antibiotics(6)
- ♦ Antiviral(6)
- ♦ Parasite(8)
- ♦ Fungal(11)
- ♦ CMV(4)
- ♦ COVID-19(3)
Others
- ♦ Biochemical Assay Reagents(19)
- ♦ Fluorescent Dye(37)
- ♦ Amino Acid Derivatives(1)
- ♦ LOX-1(1)
- ♦ gp120/CD4 (1)
- ♦ FXR(0)
- ♦ PKA (0)
- ♦ Thrombin (0)
- ♦ Liver X receptor (0)
- ♦ IL Receptor (0)
- ♦ Others 1(58)
- ♦ Others 2(86)
- ♦ Others 3(17)
- ♦ Others 4(41)
- ♦ Others 5(39)
- ♦ Others 6(155)
- ♦ Others 7(47)
New Products
- ♦ New1(23460)
- ♦ New2(6873)
- ♦ New3(9464)
- ♦ New4(21)
- ♦ New5(14)
- ♦ New6(3)
- ♦ New7(9)
- ♦ New8(10)
- ♦ New8(10)
- ♦ New9(2)
- ♦ New10(3)
- ♦ New11(10)
Immunology/Inflammation
- ♦ STING(22)
- ♦ Glucocorticoid Receptor(16)
- ♦ Arginase(3)
- ♦ TLR(31)
- ♦ IRAK(9)
- ♦ Reactive Oxygen Species(33)
- ♦ ROS(7)
- ♦ COX(36)
- ♦ Prostaglandin Receptor(2)
- ♦ MIF(1)
- ♦ Nrf2(4)
- ♦ AKR1C(2)
- ♦ Antibiotics(1)
- ♦ Galectin(2)
- ♦ IFN(1)
- ♦ SPHK(6)
- ♦ Interleukins(11)
- ♦ NO Synthase(7)
- ♦ PGE synthase(8)
- ♦ SIK(3)
- ♦ Immunology & Inflammation related(13)
- ♦ PKR(1)
- ♦ PD-1/PD-L1(10)
- ♦ NLRP3(1)
- ♦ Complement System(9)
- ♦ TBK1(2)
- ♦ NFAT(1)
- ♦ cGAS(1)
- ♦ LTR(2)
- ♦ AP-1(2)
- ♦ NLR(4)
- ♦ FLAP(5)
- ♦ Aryl Hydrocarbon Receptor(5)
- ♦ Thrombopoietin Receptor(5)
- ♦ MALT(1)
- ♦ MyD88(1)
- ♦ CD28(1)
ADC Related
- ♦ ADC Linker(15)
- ♦ ADC Cytotoxin(7)
- ♦ Drug-Linker Conjugates for ADC(10)
Metabolic Enzyme/Protease
- ♦ Phosphodiesterase(PDE)(44)
- ♦ Aminopeptidase(5)
- ♦ Endogenous Metabolite(110)
- ♦ Phospholipase(15)
- ♦ ALDH(3)
- ♦ Cytochrome P450(21)
- ♦ Dipeptidyl Peptidase(6)
- ♦ Drug Metabolite(32)
- ♦ Farnesyl Transferase(5)
- ♦ HIF/HIF Prolyl-Hydroxylase(16)
- ♦ Lactate Dehydrogenase(4)
- ♦ Mitochondrial Metabolism(14)
- ♦ MMP(16)
- ♦ PAI-1(5)
- ♦ PDI(2)
- ♦ RAR/RXR(12)
- ♦ REV-ERB(2)
- ♦ ROR(5)
- ♦ Thrombin(6)
- ♦ 11β-HSD(5)
- ♦ MAGL(5)
- ♦ TrxR(1)
- ♦ Tyrosinase(6)
- ♦ Glucokinase(5)
- ♦ Phosphatase(28)
- ♦ Aldose Reductase(8)
- ♦ Carbonic Anhydrase(1)
- ♦ Epoxide Hydrolase(4)
- ♦ Mineralocorticoid Receptor(3)
- ♦ ACE(6)
- ♦ SCD(7)
- ♦ FXR(5)
- ♦ LXR(12)
- ♦ DGK(1)
- ♦ FTO(2)
- ♦ DHODH(1)
- ♦ HMGCR(5)
- ♦ FASN(9)
- ♦ Renin(2)
- ♦ Liposome(8)
- ♦ NADPH Oxidase(6)
- ♦ Glucosidase(11)
- ♦ HIV Protease(1)
- ♦ Factor Xa(6)
- ♦ Acyltransferase(5)
- ♦ Glutathione Peroxidase(5)
- ♦ Gutathione S-transferase(2)
- ♦ 5 alpha Reductase(2)
- ♦ Tryptophan Hydroxylase(3)
- ♦ Procollagen C Proteinase(1)
- ♦ Dopamine β-hydroxylase(2)
- ♦ NEDD8-activating Enzyme(3)
- ♦ Reactive Oxygen Species(1)
- ♦ Adenosine Deaminase(2)
- ♦ Acetyl-CoA Carboxylase(4)
- ♦ ATP Citrate Lyase(3)
- ♦ IDO(2)
- ♦ MTHFD(1)
- ♦ Neprilysin(2)
- ♦ PHGDH(1)
- ♦ Proteasome(5)
- ♦ Ser/Thr Protease(3)
- ♦ PREP(2)
- ♦ Elastase(8)
- ♦ IDH(5)
- ♦ Adiponectin Receptor(1)
- ♦ Dihydroorotate Dehydrogenase(4)
- ♦ ATGL(1)
- ♦ Cathepsin(2)
- ♦ FBPase(1)
- ♦ GSNOR(1)
- ♦ Ceramidase(1)
- ♦ Hexokinase(1)
- ♦ HIV Integrase(1)
- ♦ Pyruvate Kinase(1)
- ♦ Xanthine Oxidase(1)
- ♦ E1/E2/E3 Enzyme(1)
Anti-infection
- ♦ HSV(8)
- ♦ Fungal(45)
- ♦ Influenza Virus(34)
- ♦ Bacterial(272)
- ♦ HBV(16)
- ♦ HCV Protease(5)
- ♦ HIV(29)
- ♦ RABV(1)
- ♦ Parasite(43)
- ♦ Antibiotic(16)
- ♦ Reverse Transcriptase(4)
- ♦ Virus Protease(3)
- ♦ SARS-CoV(19)
- ♦ RSV(2)
- ♦ CMV(3)
- ♦ Gli(1)
- ♦ Arenavirus(1)
- ♦ HCV(0)
- ♦ Enterovirus(6)
- ♦ HCV(26)
- ♦ Filovirus(3)
Vitamin D Related/Nuclear Receptor
- ♦ Progesterone Receptor(8)
- ♦ Glucocorticoid Receptor(2)
- ♦ ERR(30)
- ♦ Thyroid Hormone Receptor(6)
- ♦ Androgen Receptor(14)
- ♦ VD/VDR(19)
PROTAC
- ♦ PROTAC Linkers(44)
- ♦ E3 Ligase Ligand-Linker Conjugates(7)
- ♦ Ligands for E3 Ligase(11)
- ♦ Ligands for Target Protein for PROTAC(2)
- ♦ ATTECs(1)
- ♦ Molecular Glues(2)
Unfolded Protein Response
- ♦ Deubiquitinase(4)
- ♦ IRE1(8)
- ♦ PDI(1)
- ♦ Eukaryotic Initiation Factor(2)
Methylation
- ♦ NNMT(1)

Product Type
Natural Products
- ♦ Plants(54)
- ♦ Disease Research Fields(50)
- ♦ Alkaloids(3)
- ♦ Terpenoids(1)
- ♦ Phenols(1)
- ♦ Flavonoids(1)
- ♦ Natural Products 1(421)
Peptides
- ♦ Peptides 1(2018)
Antibodies
Amino Acids
- ♦ Amino Acids 1(389)
PROTACs
- ♦ PROTACs 1(60)
Fine Intermediates/Building Blocks
Others

STF-083010

Catalog No： V1900

CAS No. (CAS Registry Number)： 307543-71-1

Price： $0/g

Description: STF-083010 (formerly IRE1 Inhibitor I) is a novel and specific small-molecule inhibitor of IRE1α endonuclease. Activation of the adaptive Ire1-XBP1 pathway has been identified in man...

4μ8C (IRE1 Inhibitor III)

Catalog No： V1952

CAS No. (CAS Registry Number)： 14003-96-4

Price： $0/g

Description: 4μ8C (also known as IRE1 Inhibitor III) is a potent and selective IRE1 Rnase inhibitor (IC50 = 76 nM) with the potential for metabolic diseases. 4μ8C blocks substrate(RIDD) acce...

IXA-4

Catalog No： V3379

CAS No. (CAS Registry Number)： 1185329-96-7

Price： $0/g

Description: IXA-4 is a highly selective, non-toxic IRE1/XBP1s activator.

GSK2850163

Catalog No： V3537

CAS No. (CAS Registry Number)： 2121989-91-9

Price： $0/g

Description: GSK2850163 is a novel and potent inhibitor of inositol-requiring enzyme-1 alpha (IRE1α) which can inhibit IRE1α kinase activity and RNase activity with IC50s...

GNE-6640

Catalog No： V3858

CAS No. (CAS Registry Number)： 2009273-67-8

Price： $0/g

Description: GNE-6640, an analog of GNE-6776, is a novel potent and selective inhibitor of USP7 (ubiquitin-specific protease-7). It induces tumour cell death and enhances cytotoxic...

GNE-6776 HCl

Catalog No： V3859

CAS No. (CAS Registry Number)： 2009273-60-1

Price： $0/g

Description: GNE-6776 HCl (GNE6776), the hydrochloride salt of GNE-6776 which is an analog of GNE-6640, is a novel potent and selective inhibitor of USP7 (ubiquitin-specific protea...

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