p97 - InvivoChem

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Signaling Pathways
Apoptosis
- ♦ Bcl-2(14)
- ♦ p53(11)
- ♦ Caspase(12)
- ♦ TNFa(12)
- ♦ Mdm2(17)
- ♦ c-RET(4)
- ♦ IAP(6)
- ♦ PERK(4)
- ♦ PD-1/PD-L1(15)
- ♦ Survivin(1)
- ♦ Apoptosis(1)
PI3K/Akt/mTOR
- ♦ PI3K (64)
- ♦ Akt (22)
- ♦ mTOR (21)
- ♦ GSK-3 (17)
- ♦ ATM/ATR (0)
- ♦ PDK-1 (4)
- ♦ S6 kinase (6)
- ♦ AMPK (8)
- ♦ DNA-PK (3)
Epigenetics
- ♦ HDAC(3)
- ♦ HIF(7)
- ♦ PARP(0)
- ♦ JAK(33)
- ♦ Aurora Kinase(23)
- ♦ Histone Acetyltransferase (6)
- ♦ Histone Demethylase(10)
- ♦ Histone Methyltransferase (29)
- ♦ DNA Methyltransferase(8)
- ♦ Epigenetic Reader Domain (19)
- ♦ Sirtuin (11)
- ♦ Pim (6)
MAPK
- ♦ MEK(18)
- ♦ ERK(9)
- ♦ Raf(16)
- ♦ JNK(9)
- ♦ p38 MAPK(17)
Protein Tyrosine Kinase
- ♦ VEGFR (46)
- ♦ EGFR (42)
- ♦ PDGFR(12)
- ♦ c-MET (15)
- ♦ HER-2(2)
- ♦ ALK(10)
- ♦ FLT3 (8)
- ♦ FGFR (10)
- ♦ IFG-1R(8)
- ♦ c-Kit(3)
- ♦ Tie-2(1)
- ♦ CSF-1R(2)
- ♦ TAM Receptor (6)
- ♦ Trk receptor(3)
- ♦ c-RET(0)
Angiogenesis
- ♦ VEGFR (1)
- ♦ EGFR (0)
- ♦ PDGFR (0)
- ♦ HIF (1)
- ♦ HER-2 (0)
- ♦ JAK (0)
- ♦ FLT3 (0)
- ♦ FGFR (0)
- ♦ BTK (8)
- ♦ Syk(6)
- ♦ FAK (8)
- ♦ Src (8)
- ♦ Bcr-Abl (10)
- ♦ VDA (3)
Proteases
- ♦ Proteasome (13)
- ♦ Cysteine Protease (11)
- ♦ Serine Protease(6)
- ♦ Gamma-secretase (10)
- ♦ HCV Protease (5)
- ♦ HIV Protease(7)
- ♦ MMP (6)
- ♦ DPP-4 (8)
- ♦ Caspase (0)
- ♦ Acyltransferase(1)
NF-kB
- ♦ NOD1 (2)
- ♦ IκB/IKK(15)
- ♦ NF-κB(15)
- ♦ HDAC (0)
Autophagy
- ♦ Autophagy (24)
- ♦ LRRK2 (6)
JAK/STAT
- ♦ JAK (1)
- ♦ STAT(0)
- ♦ EGFR (3)
- ♦ Pim (1)
Metabolism
- ♦ PDE (26)
- ♦ P450 (e.g. CYP) (25)
- ♦ PPAR (16)
- ♦ Phospholipase (8)
- ♦ DHFR(6)
- ♦ Dehydrogenase (19)
- ♦ HSP (20)
- ♦ Carbonic Anhydrase (16)
- ♦ MAO (0)
- ♦ FAAH (6)
- ♦ CETP(4)
- ♦ Transferase (8)
- ♦ HMG-CoA Reductase(11)
- ♦ Hydroxylase (8)
- ♦ IDO (6)
- ♦ Retinoid Receptor (5)
- ♦ Factor Xa (4)
- ♦ AhR (3)
- ♦ Ferroptosis(3)
- ♦ Casein Kinase (4)
- ♦ NAMPT (3)
- ♦ Glucosylceramide Synthase(1)
Neuronal Signaling
- ♦ 5-HT Receptor (1)
- ♦ COX (40)
- ♦ GluR (19)
- ♦ Adrenergic Receptor(1)
- ♦ AChR Receptor (56)
- ♦ Histamine Receptor (0)
- ♦ Dopamine Receptor (1)
- ♦ Opioid Receptor (0)
- ♦ GABA Receptor (3)
- ♦ P-gp (0)
- ♦ CaMK (8)
- ♦ P2 Receptor (7)
- ♦ OX Receptor (0)
- ♦ MT Receptor (0)
- ♦ BACE (2)
- ♦ Gamma-secretase (0)
- ♦ Beta Amyloid (5)
- ♦ Monoamine Oxidase(1)
Ubiquitin
- ♦ E2 conjugating (1)
- ♦ p97 (3)
- ♦ E3 Ligase (0)
- ♦ DUB (9)
- ♦ Proteasome (0)
Stem Cells/Wnt
- ♦ Hedgehog/Smoothened ROCK (1)
- ♦ ROCK(0)
- ♦ Wnt/beta-catenin (2)
- ♦ Gamma-secretase (0)
- ♦ Casein Kinase (1)
- ♦ TGF–beta/Smad (0)
- ♦ STAT (9)
- ♦ JAK (0)
- ♦ GSK-3 (0)
DNA Damage
- ♦ Telomerase(2)
- ♦ Topoisomerase (36)
- ♦ DNA/RNA Synthesis (74)
- ♦ HDAC (39)
- ♦ ATM/ATR (14)
- ♦ PARP (31)
- ♦ Sirtuin (0)
- ♦ DNA Stain(1)
GPCR & G Protein
- ♦ cAMP (2)
- ♦ Adenosine Receptor (19)
- ♦ Vasopressin Receptor (5)
- ♦ CXCR (7)
- ♦ CaSR (3)
- ♦ PAFR (2)
- ♦ CGRP Receptor (1)
- ♦ LPA Receptor (2)
- ♦ SGLT (5)
- ♦ S1P Receptor (8)
- ♦ Endothelin Receptor (7)
- ♦ Cannabinoid Receptor (9)
- ♦ 5-HT Receptor (79)
- ♦ Adrenergic Receptor (65)
- ♦ Histamine Receptor (47)
- ♦ Dopamine Receptor (39)
- ♦ Opioid Receptor (13)
- ♦ Hedgehog/Smoothened ROCK (11)
- ♦ OX Receptor (8)
- ♦ MT Receptor (2)
- ♦ Guanylate Cyclase(3)
- ♦ LPL Receptor(1)
- ♦ NPY receptor(1)
TGF-beta/Smad
- ♦ MT Receptor (20)
- ♦ Bcr-Abl (0)
- ♦ ROCK (20)
- ♦ PKC (10)
Cell Cycle
- ♦ CDK (45)
- ♦ Rho (13)
- ♦ PLK (10)
- ♦ Chk (6)
- ♦ Aurora Kinase (0)
- ♦ ROCK (2)
- ♦ PD-1/PD-L1 (0)
- ♦ c-Myc (3)
- ♦ Wee1 (1)
- ♦ APC (1)
- ♦ HSP(2)
Cytoskeletal Signaling
- ♦ Bcr-Abl(1)
- ♦ Wnt/beta-catenin (10)
- ♦ PKC (1)
- ♦ FAK(0)
- ♦ HSP (1)
- ♦ Dynamin (3)
- ♦ PAK (4)
- ♦ Integrin (9)
- ♦ Microtubule Associated(25)
- ♦ Kinesin (6)
Transmembrane
- ♦ P-gp (6)
- ♦ Proton Pump (10)
- ♦ GABA Receptor (11)
- ♦ Sodium Channel (28)
- ♦ Potassium Channel (16)
- ♦ Calcium Channel (34)
- ♦ ATPase (0)
- ♦ CRM1 (1)
- ♦ TRPV (0)
- ♦ CFTR (0)
- ♦ OCT (0)
- ♦ Amino Acid Transporter(2)
- ♦ Monocarboxylate Transporter(1)
Endocrinology & Hormones
- ♦ Opioid Receptor (0)
- ♦ Glucocorticoid Receptor(5)
- ♦ Estrogen/progestogen Receptor (43)
- ♦ Androgen Receptor (15)
- ♦ RAAS (27)
- ♦ Aromatase(5)
- ♦ GPR(8)
- ♦ 5-alpha Reductase (2)
Microbiology
- ♦ HCV Protease (1)
- ♦ HIV Protease (0)
- ♦ CCR (1)
- ♦ Reverse Transcriptase(27)
- ♦ Integrase (0)
- ♦ Bacterial(4)
- ♦ Anti-infection(0)
Others
- ♦ gp120/CD4 (2)
- ♦ FXR(4)
- ♦ PKA (2)
- ♦ Thrombin (4)
- ♦ Liver X receptor (3)
- ♦ IL Receptor (0)
- ♦ Others 1(365)
- ♦ Others 2(433)
- ♦ Others 3(331)
- ♦ Others 4(295)
- ♦ Others 5(250)
- ♦ Others 6(572)
- ♦ Others 7(232)
New Products
- ♦ New1(25335)
- ♦ New2(7404)
- ♦ New3(9983)
- ♦ New4(21)
Immunology/Inflammation
- ♦ STING(3)
- ♦ Glucocorticoid Receptor(1)
- ♦ Arginase(2)
- ♦ TLR(3)
ADC Related
- ♦ ADC Linker(3)
Metabolic Enzyme/Protease
- ♦ Phosphodiesterase(PDE)(4)
- ♦ Aminopeptidase(1)
- ♦ Endogenous Metabolite(2)
- ♦ Phospholipase(1)
Anti-infection
- ♦ HSV(1)
- ♦ Fungal(7)
- ♦ Influenza Virus(3)
- ♦ Bacterial(39)
- ♦ HBV(1)
- ♦ HCV Protease(1)
- ♦ HIV(3)
- ♦ RABV(1)
- ♦ Parasite(3)
Vitamin D Related/Nuclear Receptor
- ♦ Progesterone Receptor(1)
- ♦ Glucocorticoid Receptor(2)
- ♦ Estrogen Receptor/ERR(1)
PROTAC
- ♦ PROTAC Linkers(40)
Transmembrane Transporters
- ♦ TRP(1)
- ♦ ATPase(2)

Product Type
Natural Products
- ♦ Natural Products 1(446)
Peptides
- ♦ Peptides 1(1995)
Antibodies
Amino Acids
- ♦ Amino Acids 1(389)
PROTACs
- ♦ PROTACs 1(39)
Fine Intermediates/Building Blocks
Others

NMS-873

Catalog No： V1318

CAS No. (CAS Registry Number)： 1418013-75-8

Price： $0/g

Description: NMS-873 (also known as NMS 873, NMS873, p97 inhibitor) is a potent, allosteric and specific p97 inhibitor with potential antitumor activity. It inhibits p97 with an IC50 value of 30 ...

DBeQ (JRF 12)

Catalog No： V1319

CAS No. (CAS Registry Number)： 177355-84-9

Price： $0/g

Description: DBeQ (JRF-12; JRF 12; JRF12) is a reversible and ATP-competitive p97 inhibitor with potential antineoplastic activity. It inhibits p97 with an IC50 of 1.5 μM. DBeQ can be used f...

MNS (NSC 170724, MDBN)

Catalog No： V1320

CAS No. (CAS Registry Number)： 1485-00-3

Price： $0/g

Description: MNS (NSC170724; NSC-170724; NSC 170724; 5-(2-Nitrovinyl)benzodioxole)) is a novel, potent and selective TKI-tyrosine kinase inhibitor with anti-platelet activity. It inhibits multipl...

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