Sodium Picosulfate

别名: Sodium picosulphateSodium Picosulfate LA 391 Laxidogol Natrii picosulfas Picosulfate sodium Guttalax 匹可硫酸钠;匹可硫酸钠(匹可速发);匹可硫酸钠(匹克硫酸钠); 4,4'-(吡啶-2-基亚甲基)双苯基双硫酸酯钠盐;匹克硫酸钠;吡苯氧磺钠;
目录号: V11608 纯度: ≥98%
匹可硫酸钠是一种泻药,用于结肠镜检查前清洁结肠,通过抑制水和电解质的吸收并增加其分泌来发挥作用。
Sodium Picosulfate CAS号: 10040-45-6
产品类别: New12
产品仅用于科学研究,不针对患者销售
规格 价格 库存 数量
250mg
500mg
1g
2g
Other Sizes
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InvivoChem产品被CNS等顶刊论文引用
产品描述
匹可硫酸钠是一种泻药,用于结肠镜检查前清洁结肠,通过抑制水和电解质的吸收并增加其分泌来发挥作用。作为泻药,也可用于治疗便秘。它刺激肠道内的运动,有助于促进粪便通过。它还与其他药物一起用于结肠镜检查或手术前的肠道清洁。该药有口服溶液、片剂、糖浆等不同剂型。
生物活性&实验参考方法
毒性/毒理 (Toxicokinetics/TK)
妊娠期和哺乳期影响
◉ 哺乳期用药概述
匹可硫酸钠不被胃肠道吸收,其被吸收的活性代谢物在母乳中检测不到。哺乳期妇女可以服用匹可硫酸钠,无需特殊注意事项。
◉ 对母乳喂养婴儿的影响
截至修订日期,未找到相关的已发表信息。
◉ 对泌乳和母乳的影响
截至修订日期,未找到相关的已发表信息。
参考文献

[1].Toxicity study with sodium picosulfate in cultured liver cells of rabbit, rat and man. Arzneimittelforschung, 1981. 31(2): p. 321-5.

[2].Effects of 'contact laxatives' on intestinal and colonic epithelial cell proliferation. Pharmacology, 1993. 47 Suppl 1: p. 187-95.

[3].In vivo motility of rat colon chronically pretreated with sennosides. Pharmacology, 1993. 47 Suppl 1: p. 155-61.

其他信息
匹可硫酸钠是一种芳基硫酸盐,属于吡啶类化合物。
*注: 文献方法仅供参考, InvivoChem并未独立验证这些方法的准确性
化学信息 & 存储运输条件
分子式
C18H13NNA2O8S2
分子量
481.4
精确质量
480.9878
CAS号
10040-45-6
PubChem CID
68654
外观&性状
Typically exists as solid at room temperature
熔点
272 - 275ºC
LogP
4.101
tPSA
162.51
氢键供体(HBD)数目
0
氢键受体(HBA)数目
9
可旋转键数目(RBC)
5
重原子数目
31
分子复杂度/Complexity
633
定义原子立体中心数目
0
SMILES
S(=O)(=O)([O-])OC1C([H])=C([H])C(=C([H])C=1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=N1)C1C([H])=C([H])C(=C([H])C=1[H])OS(=O)(=O)[O-].[Na+].[Na+]
InChi Key
GOZDTZWAMGHLDY-UHFFFAOYSA-L
InChi Code
InChI=1S/C18H15NO8S2.2Na/c20-28(21,22)26-15-8-4-13(5-9-15)18(17-3-1-2-12-19-17)14-6-10-16(11-7-14)27-29(23,24)25/h1-12,18H,(H,20,21,22)(H,23,24,25)/q2*+1/p-2
化学名
4,4'-(2-Picolylidene)bis(phenylsulfuric acid) disodium salt
别名
Sodium picosulphateSodium Picosulfate LA 391 Laxidogol Natrii picosulfas Picosulfate sodium Guttalax
HS Tariff Code
2934.99.9001
存储方式

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

注意: 请将本产品存放在密封且受保护的环境中,避免吸湿/受潮。
运输条件
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
溶解度数据
溶解度 (体外实验)
DMSO : ~100 mg/mL (~207.72 mM)
H2O : ≥ 100 mg/mL (~207.72 mM)
溶解度 (体内实验)
配方 1 中的溶解度: ≥ 2.5 mg/mL (5.19 mM) (饱和度未知) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (这些助溶剂从左到右依次添加,逐一添加), 澄清溶液。
例如,若需制备1 mL的工作液,可将100 μL 25.0 mg/mL澄清DMSO储备液加入到400 μL PEG300中,混匀;然后向上述溶液中加入50 μL Tween-80,混匀;加入450 μL生理盐水定容至1 mL。
*生理盐水的制备:将 0.9 g 氯化钠溶解在 100 mL ddH₂O中,得到澄清溶液。

配方 2 中的溶解度: ≥ 2.5 mg/mL (5.19 mM) (饱和度未知) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (这些助溶剂从左到右依次添加,逐一添加), 澄清溶液。
例如,若需制备1 mL的工作液,可将 100 μL 25.0 mg/mL澄清DMSO储备液加入900 μL 20% SBE-β-CD生理盐水溶液中,混匀。
*20% SBE-β-CD 生理盐水溶液的制备(4°C,1 周):将 2 g SBE-β-CD 溶解于 10 mL 生理盐水中,得到澄清溶液。

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配方 3 中的溶解度: ≥ 2.5 mg/mL (5.19 mM) (饱和度未知) in 10% DMSO + 90% Corn Oil (这些助溶剂从左到右依次添加,逐一添加), 澄清溶液。
例如,若需制备1 mL的工作液,可将 100 μL 25.0 mg/mL 澄清 DMSO 储备液加入到 900 μL 玉米油中并混合均匀。


配方 4 中的溶解度: 100 mg/mL (207.72 mM) in PBS (这些助溶剂从左到右依次添加,逐一添加), 澄清溶液; 超声助溶.

请根据您的实验动物和给药方式选择适当的溶解配方/方案:
1、请先配制澄清的储备液(如:用DMSO配置50 或 100 mg/mL母液(储备液));
2、取适量母液,按从左到右的顺序依次添加助溶剂,澄清后再加入下一助溶剂。以 下列配方为例说明 (注意此配方只用于说明,并不一定代表此产品 的实际溶解配方):
10% DMSO → 40% PEG300 → 5% Tween-80 → 45% ddH2O (或 saline);
假设最终工作液的体积为 1 mL, 浓度为5 mg/mL: 取 100 μL 50 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中,混合均匀/澄清;向上述体系中加入50 μL Tween-80,混合均匀/澄清;然后继续加入450 μL ddH2O (或 saline)定容至 1 mL;

3、溶剂前显示的百分比是指该溶剂在最终溶液/工作液中的体积所占比例;
4、 如产品在配制过程中出现沉淀/析出,可通过加热(≤50℃)或超声的方式助溶;
5、为保证最佳实验结果,工作液请现配现用!
6、如不确定怎么将母液配置成体内动物实验的工作液,请查看说明书或联系我们;
7、 以上所有助溶剂都可在 Invivochem.cn网站购买。
制备储备液 1 mg 5 mg 10 mg
1 mM 2.0773 mL 10.3864 mL 20.7727 mL
5 mM 0.4155 mL 2.0773 mL 4.1545 mL
10 mM 0.2077 mL 1.0386 mL 2.0773 mL

1、根据实验需要选择合适的溶剂配制储备液 (母液):对于大多数产品,InvivoChem推荐用DMSO配置母液 (比如:5、10、20mM或者10、20、50 mg/mL浓度),个别水溶性高的产品可直接溶于水。产品在DMSO 、水或其他溶剂中的具体溶解度详见上”溶解度 (体外)”部分;

2、如果您找不到您想要的溶解度信息,或者很难将产品溶解在溶液中,请联系我们;

3、建议使用下列计算器进行相关计算(摩尔浓度计算器、稀释计算器、分子量计算器、重组计算器等);

4、母液配好之后,将其分装到常规用量,并储存在-20°C或-80°C,尽量减少反复冻融循环。

计算器

摩尔浓度计算器可计算特定溶液所需的质量、体积/浓度,具体如下:

  • 计算制备已知体积和浓度的溶液所需的化合物的质量
  • 计算将已知质量的化合物溶解到所需浓度所需的溶液体积
  • 计算特定体积中已知质量的化合物产生的溶液的浓度
使用摩尔浓度计算器计算摩尔浓度的示例如下所示:
假如化合物的分子量为350.26 g/mol,在5mL DMSO中制备10mM储备液所需的化合物的质量是多少?
  • 在分子量(MW)框中输入350.26
  • 在“浓度”框中输入10,然后选择正确的单位(mM)
  • 在“体积”框中输入5,然后选择正确的单位(mL)
  • 单击“计算”按钮
  • 答案17.513 mg出现在“质量”框中。以类似的方式,您可以计算体积和浓度。

稀释计算器可计算如何稀释已知浓度的储备液。例如,可以输入C1、C2和V2来计算V1,具体如下:

制备25毫升25μM溶液需要多少体积的10 mM储备溶液?
使用方程式C1V1=C2V2,其中C1=10mM,C2=25μM,V2=25 ml,V1未知:
  • 在C1框中输入10,然后选择正确的单位(mM)
  • 在C2框中输入25,然后选择正确的单位(μM)
  • 在V2框中输入25,然后选择正确的单位(mL)
  • 单击“计算”按钮
  • 答案62.5μL(0.1 ml)出现在V1框中
g/mol

分子量计算器可计算化合物的分子量 (摩尔质量)和元素组成,具体如下:

注:化学分子式大小写敏感:C12H18N3O4  c12h18n3o4
计算化合物摩尔质量(分子量)的说明:
  • 要计算化合物的分子量 (摩尔质量),请输入化学/分子式,然后单击“计算”按钮。
分子质量、分子量、摩尔质量和摩尔量的定义:
  • 分子质量(或分子量)是一种物质的一个分子的质量,用统一的原子质量单位(u)表示。(1u等于碳-12中一个原子质量的1/12)
  • 摩尔质量(摩尔重量)是一摩尔物质的质量,以g/mol表示。
/

配液计算器可计算将特定质量的产品配成特定浓度所需的溶剂体积 (配液体积)

  • 输入试剂的质量、所需的配液浓度以及正确的单位
  • 单击“计算”按钮
  • 答案显示在体积框中
动物体内实验配方计算器(澄清溶液)
第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量)
第二步:请输入动物体内配方组成(配方适用于不溶/难溶于水的化合物),不同的产品和批次配方组成不同,如对配方有疑问,可先联系我们提供正确的体内实验配方。此外,请注意这只是一个配方计算器,而不是特定产品的确切配方。
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计算结果:

工作液浓度 mg/mL;

DMSO母液配制方法 mg 药物溶于 μL DMSO溶液(母液浓度 mg/mL)。如该浓度超过该批次药物DMSO溶解度,请首先与我们联系。

体内配方配制方法μL DMSO母液,加入 μL PEG300,混匀澄清后加入μL Tween 80,混匀澄清后加入 μL ddH2O,混匀澄清。

(1) 请确保溶液澄清之后,再加入下一种溶剂 (助溶剂) 。可利用涡旋、超声或水浴加热等方法助溶;
            (2) 一定要按顺序加入溶剂 (助溶剂) 。

临床试验信息
Title:Comparison of 1 Liter PEG With Ascorbate and Sodium Picosulfate / Magnesium Citrate for High Quality Colon Cleansing
Status:Completed
updateDate:2026-05-14
Ctid:NCT04598880

Link: https://clinicaltrials.gov/ct2/show/NCT04598880

Conditions:Colonic Diseases
Interventions:Sodium picosulfate + magnesium citrate
Phase:Phase 4
Title:A Study to Investigate Bowel Cleansing With PLENVU® Compared to Sodium Picosulfate in Participants Aged 1 to < 18 Years of Age in Preparation for Colonoscopy
Status:Recruiting
updateDate:2026-01-21
Ctid:NCT07218523

Link: https://clinicaltrials.gov/ct2/show/NCT07218523

Conditions:Bowel Cleansing Prior to Clinical Procedures
Interventions:Sodium picosulfate
Phase:Phase 3
Title:A Trial to Compare Efficacy and Tolerability of Plenvu® and Picoprep® as Cleansing Agents Before Colonoscopy
Status:Recruiting
updateDate:2024-11-19
Ctid:NCT05436054

Link: https://clinicaltrials.gov/ct2/show/NCT05436054

Conditions:Colon Disease
Interventions:Plenvu
Phase:Phase 4
View More

Title:TES RCT Fleet Enema vs Oral Mechanical Bowel Prep
Status:Recruiting
updateDate:2024-08-27
Ctid:NCT05148494

Link: https://clinicaltrials.gov/ct2/show/NCT05148494

Conditions:Colorectal Neoplasms|Surgery
Interventions:Pico-Salax
Phase:Phase 4
Title:Bowel Preparation Regimen for Colon Capsule Endoscopy Procedure
Status:Completed
updateDate:2024-02-28
Ctid:NCT05726097

Link: https://clinicaltrials.gov/ct2/show/NCT05726097

Conditions:Colon Cancer|Inflammatory Bowel Diseases|Gastrointestinal Bleed|Colon Polyp
Interventions:prucalopride
Phase:Phase 3
Title:Lubiprostone for Functional Constipation in the Under 18 Years Patients
Status:Completed
updateDate:2022-11-15
Ctid:NCT05144295

Link: https://clinicaltrials.gov/ct2/show/NCT05144295

Conditions:Clinical Efficacy|Treatment Efficacy|Drug Side Effect
Interventions:Sodium Picosulfate
Phase:Phase 3
Title:Difference of Surgical Site Infection Between Using Sodium Picosulfate Solution(PicosolutionⓇ) and Oral Sulfate Tablet(ORA·FANGⓇ) in Colorectal Cancer Surgery
Status:Unknown status
updateDate:2020-10-20
Ctid:NCT04593446

Link: https://clinicaltrials.gov/ct2/show/NCT04593446

Conditions:Colorectal Cancer
Interventions:Sodium Picosulfate Solution(PicosolutionⓇ)
Phase:Phase 2
Title:Study of Different Endoscopic Preparations Used in Pediatric Colonoscopy
Status:Unknown status
updateDate:2019-11-08
Ctid:NCT04153084

Link: https://clinicaltrials.gov/ct2/show/NCT04153084

Conditions:Digestive Illness
Interventions:Sodium picosulfate
Phase:
Title:The Efficacy of Chewing Gums Versus Laxative in Early Return of Bowel Function After CS
Status:Unknown status
updateDate:2019-09-23
Ctid:NCT02765971

Link: https://clinicaltrials.gov/ct2/show/NCT02765971

Conditions:Intestinal Recovery After Cesarean Section
Interventions:normal saline
Phase:Phase 4
Title:Aquanet Bowel Cleansing Device Versus Oral Sodium Picosulfate for Pre-endoscopy Bowel Preparation
Status:Completed
updateDate:2017-03-08
Ctid:NCT03074448

Link: https://clinicaltrials.gov/ct2/show/NCT03074448

Conditions:Bowel Preparation
Interventions:Sodium Picosulfate
Phase:Phase 3
Title:A Trial Comparing the PICOPREP Tailored Dosing Schedule to the PICOPREP Day-before Dosing Schedule for Colon Cleansing in Preparation for Colonoscopy
Status:Completed
updateDate:2016-06-23
Ctid:NCT02239692

Link: https://clinicaltrials.gov/ct2/show/NCT02239692

Conditions:Bowel Cleansing
Interventions:PICOPREP
Phase:Phase 3
Title:Comparing Bowel Preparation Regimens for Flexible Sigmoidoscopy
Status:Completed
updateDate:2015-09-25
Ctid:NCT01554111

Link: https://clinicaltrials.gov/ct2/show/NCT01554111

Conditions:Cathartic Colon
Interventions:Pico-Salax and Sodium phosphate enema
Phase:Phase 4
Title:Pico-Salax Colonic Preparation Study: Quantifying Electrolyte and Volume Status Changes
Status:Completed
updateDate:2015-09-22
Ctid:NCT00885430

Link: https://clinicaltrials.gov/ct2/show/NCT00885430

Conditions:Hemodynamics|Hyponatremia
Interventions:Pico-Salax
Phase:Phase 4
Title:A Randomized Controlled Trial Comparing Two Timing Regimens of Pico-salax for Colon Cleansing Prior to Colonoscopy
Status:Completed
updateDate:2015-08-31
Ctid:NCT00885274

Link: https://clinicaltrials.gov/ct2/show/NCT00885274

Conditions:Colonoscopy
Interventions:Split Dose Pico-Salax
Phase:Phase 4
Title:A Multi-centre Study Comparing the Polyp Detection Rate of Two Different Types of Bowel Preparation: a 2-litre Solution (MOVIPREP®) Versus a Hyperosmotic and Stimulant Combined Low Volume Bowel Preparation (Sodium Picosulfate and Magnesium Citrate)
Status:Completed
updateDate:2015-03-31
Ctid:NCT01689792

Link: https://clinicaltrials.gov/ct2/show/NCT01689792

Conditions:Colorectal Cancer
Interventions:CitraFleet
Phase:Phase 4
Title:Pharmacokinetics of Bisacodyl or Sodium Picosulfate Administered Orally in Healthy Lactating Females
Status:Completed
updateDate:2014-08-08
Ctid:NCT02211911

Link: https://clinicaltrials.gov/ct2/show/NCT02211911

Conditions:Healthy
Interventions:Sodium picosulfate
Phase:Phase 1
Title:Sodium Picosulphate vs. Placebo in Functional Constipation
Status:Completed
updateDate:2014-05-16
Ctid:NCT00576810

Link: https://clinicaltrials.gov/ct2/show/NCT00576810

Conditions:Constipation
Interventions:sodium picosulphate
Phase:Phase 3
Title:Investigation of PicoPrep Versus HalfLytely for Bowel Preparation for Colonoscopy - Split Dose PicoPrep
Status:Completed
updateDate:2013-02-12
Ctid:NCT01073930

Link: https://clinicaltrials.gov/ct2/show/NCT01073930

Conditions:Bowel Preparation
Interventions:bisacodyl
Phase:Phase 3
Title:Colonoscopy Preparation Optimization for INpatients- COIN Study
Status:Unknown status
updateDate:2013-01-30
Ctid:NCT01627171

Link: https://clinicaltrials.gov/ct2/show/NCT01627171

Conditions:Endoscopy|Bowel Preparation Solutions
Interventions:Picosulfate sodium
Phase:Phase 4
Title:Investigation of PICOPREP and PEG-ELS for Bowel Preparation for Colonoscopy
Status:Completed
updateDate:2013-01-28
Ctid:NCT01356407

Link: https://clinicaltrials.gov/ct2/show/NCT01356407

Conditions:Colonoscopy
Interventions:PEG-ELS
Phase:Phase 3
Title:Investigation of PicoPrep Versus HalfLytely for Bowel Preparation for Colonoscopy - Day Before PicoPrep
Status:Completed
updateDate:2012-10-30
Ctid:NCT01073943

Link: https://clinicaltrials.gov/ct2/show/NCT01073943

Conditions:Bowel Preparation
Interventions:bisacodyl
Phase:Phase 3
Title:A Study of PICOPREP in Patients Needed to Clean the Bowel Prior to X-ray Examination, Endoscopy or Surgery.
Status:Completed
updateDate:2012-02-09
Ctid:NCT01292109

Link: https://clinicaltrials.gov/ct2/show/NCT01292109

Conditions:Bowel Cleanliness
Interventions:sodium picosulphate
Phase:
Title:Efficacy and Safety of Polyethylene Glycol Compared With Sodium Picosulphate for Bowel Preparation Before Colonoscopy
Status:Unknown status
updateDate:2010-03-25
Ctid:NCT01093274

Link: https://clinicaltrials.gov/ct2/show/NCT01093274

Conditions:Bowel Preparation
Interventions:Polyethylene Glycol
Phase:N/A
Title:Efficacy, Safety and Tolerability of CitraFleet, a New Bowel Cleansing Agent-a Prospective, Single-Center, Single-Group Phase IV Study
Status:Completed
Date:2018-11-07
Eudractnumber:2018-003257-16

Link: https://www.clinicaltrialsregister.eu/ctr-search/search?query=2018-003257-16

Condition:Colonoscopy bowel preparationKolonoszkópia előkészítés
Phase:Phase 4
Title:Unilateral, open and randomized phase IV study of 2 groups to assess the degree of comfort with simple Emuliquen® in patients undergoing proctological surgery
Status:Completed
Date:2017-12-11
Eudractnumber:2017-002811-33

Link: https://www.clinicaltrialsregister.eu/ctr-search/search?query=2017-002811-33

Condition:Surgery proctologicalcirugía proctológica
Phase:Phase 4
Title:A randomised, assessor-blinded, multi-centre trial comparing the efficacy, safety and tolerability of the PICOPREP tailored dosing schedule to the PICOPREP day-before dosing schedule for colon cleansing in preparation for colonoscopy
Status:Completed
Date:2014-11-03
Eudractnumber:2014-001062-10

Link: https://www.clinicaltrialsregister.eu/ctr-search/search?query=2014-001062-10

Condition:Bowel cleansing
Phase:Phase 3
Title:A Multicenter Randomized Parallel Group Phase III Study Comparing the Bowel Cleansing Efficacy, Safety and Tolerability of NER1006 (a Low Volume Bowel Cleansing Solution) versus a Sodium Picosulfate and Magnesium Salt (SP+MS) Solution Using a Day Before-Only Dosing Regimen in Adults
Status:Completed
Date:2014-10-10
Eudractnumber:2014-002186-30

Link: https://www.clinicaltrialsregister.eu/ctr-search/search?query=2014-002186-30

Condition:Bowel cleansing prior to any procedure that requires a clean bowel, e.g. colonoscopy, surgical, video capsule or radiological procedures.
Phase:Phase 3
Title:Randomized, multicentre, single blind study to evaluate the effectiveness of two administration schedules of CitraFleet (sodium picosulfate plus magnesium citrate) to cleanse the colon
Status:Completed
Date:2013-07-29
Eudractnumber:2013-001620-20

Link: https://www.clinicaltrialsregister.eu/ctr-search/search?query=2013-001620-20

Condition:Cleansing of colonReinigung des Darmes
Phase:Phase 3
Title:Title : COMPARISON OF THE EFFECTIVENESS OF TWO PROTOCOLS FOR BOWEL CLEANING FOR CAPSULE ENDOSCOPY STUDIO
Status:Ongoing
Date:2013-07-10
Eudractnumber:2012-005754-38

Link: https://www.clinicaltrialsregister.eu/ctr-search/search?query=2012-005754-38

Condition:We do not use these products in a concrete disease. We compare the effectiveness of these products to obtain an accurate bowel cleansing before performing a capsule endoscopic study.No usamos estos productos en una patología en concreto, sino que nuestro objetivo es comparar la eficacia de ambos para obtener una adecuada limpieza intestinal en aquellos pacientes que van a ser sometidos a un estudio con cápsula endoscópica
Phase:Phase 4
Title:A RANDOMISED, PLACEBO-CONTROLLED, CROSSOVER STUDY TO COMPARE THE EFFECT OF SODIUM PICOSULFATE AND PRUCALOPRIDE ON COLONIC SENSORY AND MOTOR RESPONSE TO DISTENSION IN HEALTHY SUBJECTS
Status:Completed
Date:2013-05-28
Eudractnumber:2012-004367-44

Link: https://www.clinicaltrialsregister.eu/ctr-search/search?query=2012-004367-44

Condition:SENSORY AND MOTOR RESPONSE OF DESCENDING COLON TO DISTENSION WILL BE STUDIED IN HEALTHY SUBJECTS
Phase:Phase 4
Title:PicoPrep versus KleanPrep: Efficacy and patient satisfaction of bowel preparation products before colonoscopy. A single-blinded randomised trial.
Status:Ongoing
Date:2012-12-05
Eudractnumber:2012-004327-21

Link: https://www.clinicaltrialsregister.eu/ctr-search/search?query=2012-004327-21

Condition:bowel preparation before colonoscopydarmreiniging voor coloscopie
Phase:Phase 4
Title:Randomized controlled trial: Picoprep versus Moviprep for efficacy, safety and patient tolerability in colonoscopy bowel preparation.
Status:Ongoing
Date:2012-09-10
Eudractnumber:2011-004384-75

Link: https://www.clinicaltrialsregister.eu/ctr-search/search?query=2011-004384-75

Condition:Patients who need a colonoscopy for screening, surveillance or diagnosis of a disease have to be prepared by bowel cleansingPatienten die een coloscopie moeten ondergaan vanwege screening, opvolging of diagnose van een ziekte moeten darmvoorbereiding krijgen
Phase:Phase 4
Title:A multi-centre, randomised, investigator-blinded study comparing the polyp detection rate of two different types of bowel preparation: a 2-litre solution (MOVIPREP®) versus a hyperosmotic and stimulant combined low volume bowel preparation (Sodium Picosulfate and Magnesium Citrate)
Status:Completed
Date:2011-10-31
Eudractnumber:2011-002364-25

Link: https://www.clinicaltrialsregister.eu/ctr-search/search?query=2011-002364-25

Condition:Patients with clinical symptoms or polyp history scheduled for either a diagnostic/surveillance colonoscopy or for a screening procedure in patients with a personal or familial risk of colon neoplasia.
Phase:Phase 4
Title:SODIUM PICOSULPHATE AND MAGNESIUM CITRATE VERSUS POLYETHYLENE GLYCOLE (PEG) AS EVACUATING TREATMENT PRIOR TO COLONOSCOPY:
Status:Completed
Date:2011-05-04
Eudractnumber:2011-000587-10

Link: https://www.clinicaltrialsregister.eu/ctr-search/search?query=2011-000587-10

Condition:� Subjects who are candidate to undergo colonoscopy:� Diagnosis� Screening� Follow-up after previous polipectomy
Phase:Phase 4
Title:A Study into the Effect of Mechanical Bowel Preparation on Aerobic Exercise Capacity as Measured by Cardiopulmonary Exercise Testing.
Status:Completed
Date:2010-02-22
Eudractnumber:2009-016874-34

Link: https://www.clinicaltrialsregister.eu/ctr-search/search?query=2009-016874-34

Condition:We are investigating the effect of mechanical bowel preparation, such as Picolax, on aerobic exercise capacity in healthy volunteers.
Phase:Phase 4
Title:A prospective, randomised study comparing a 3-sachet Picolax® treatment with the standard 2-sachet Picolax® for bowel cleansing prior to colonoscopy.
Status:Prematurely Ended
Date:2008-11-24
Eudractnumber:2007-003735-23

Link: https://www.clinicaltrialsregister.eu/ctr-search/search?query=2007-003735-23

Condition:Bowel preparation prior to elective complete colonoscopy.As 'bowel preparation' is not a specific medical condition, there is no MedDRA term.
Phase:Phase 3
Title:ESTUDIO EN FASE III, CIEGO, ALEATORIZADO, MULTICÉNTRICO, PARA LA EVALUACIÓN DE SEGURIDAD Y EFICACIA DEL CITRAFLEET® (PICOSULFATO SÓDICO) COMO TRATAMIENTO EVACUANTE PREVIO A EXPLORACIÓN ENDOSCÓPICA COLÓNICA.
Status:Completed
Date:2007-10-26
Eudractnumber:2007-001834-15

Link: https://www.clinicaltrialsregister.eu/ctr-search/search?query=2007-001834-15

Condition:Pacientes de ambos sexos a los que se les vaya a realizar una exploración endoscópica colónica que precisara evacuación intestinal previa
Phase:Phase 3
Title:A randomised, double -blind, placebo-controlled, parallel group study to assess the efficacy and safety of 4 weeks treatment with sodium picosulphate Dulcolax®, Laxoberal® drops 10 mg administered orally, once daily, in patients with functional constipation.
Status:Completed
Date:2007-08-28
Eudractnumber:2007-002087-10

Link: https://www.clinicaltrialsregister.eu/ctr-search/search?query=2007-002087-10

Condition:To compare the efficacy and safety of 4 weeks treatment with sodium picosulphate Dulcolax®, Laxoberal® drops to placebo in patients with functional constipation
Phase:Phase 3
Title:A randomised, single-centre, single-blind,parallel group, pilot study to assess the efficacy, safety and patient acceptability of a new 2-litre bowel preparation agent (Moviprep) compared to a standard bowel preparation agent (Picolax)
Status:Completed
Date:2005-07-26
Eudractnumber:2004-001487-43

Link: https://www.clinicaltrialsregister.eu/ctr-search/search?query=2004-001487-43

Condition:Gut cleansing prior to colonoscopy procedure
Phase:Phase 2

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